Cell-based assays (iLite®)

iLite technology is based upon a reporter gene assay format, modified and adapted for applications during the whole drug development cycle as well as for monitoring of biological drugs.

iLite cell lines can be developed for any biopharmaceutical target and assays for drug potency, i.e. drug activity, and neutralizing antibodies (NAbs) can easily be set-up using the same cell line. All cell lines are supplied as Assay Ready Cells, which does not need culturing, and can be used straight from the freezer. 

Product 

Regulatory Status

ASSAY READY CELLS 

 
BM5001 iLite® ADCC Effector (V) RUO
BM5011 iLite® ADCC Target HER2 (+) RUO
BM5016 iLite® ADCC Target HER2 (-) RUO
BM5013 iLite® ADCC Target mTNF-alpha (+) RUO
BM5014 iLite® ADCC Target mTNF-alpha (-) RUO
BM5035 iLite® ADCC Target EGFR (+) RUO
BM5036 iLite® ADCC Target EGFR (-) RUO
BM3044 iLite® TNF-alpha  RUO
BM3049 iLite® Type I IFN RUO
BM3060 iLite® Insulin  RUO
BM3071 iLite® FGF21 RUO
BM4023 iLite® IL-23  RUO
BM4012 iLite® IL-12  RUO
BM4050 iLite® GM-CSF RUO
BM4021 iLite® VEGF RUO
     

ADCC ACTIVITY SETS

 
BM5080 iLite® anti-EGFR ADCC Activity Set RUO
BM5090 iLite® anti-HER2 ADCC Activity Set RUO
BM5095 iLite® anti-mTNF-alpha ADCC Activity Set RUO
     

REAGENTS

 

TNF-alpha reagents

 
BM3133 iLite® TNF-alpha (16 ng/mL) RUO
BM3136 iLite® Infliximab NAb positive control RUO
BM3159 iLite® Adalimumab NAb positive control RUO
BM3177 iLite® Etanercept NAb positive control RUO
BM3132 iLite® Diluent A RUO
BM3134 iLite® Diluent B RUO
BM3139 iLite® Diluent C RUO
BM3135 iLite® Reagents BLANK RUO
     

IFN reagents

 
BM3249 iLite® IFN beta 1a (950 IU-mL) RUO
BM3250 iLite® Diluent D RUO
BM3251 iLite® IFN beta 1a NAb positive control RUO


*For research use only (RUO). These products are intended for professional research use only. The data and results originating from using the products, should not be used either in diagnostic procedures or in human therapeutic applications.

In accepting delivery of iLite® Assay Ready Cells the recipient agrees not to sub-culture these cells, attempt to sub-culture them or to give them to a third party, and recipient is only to use them directly in assays. iLite®  cell-based products are covered by patents which are the property of Svar Life Science AB and any attempt to reproduce the delivered iLite®  Assay Ready Cells would constitute an infringement.